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The Lord himself shall descend from heaven with a shout, with the voice of the archangel, and with the trump of God: and the dead in Christ shall rise first: 4:16
Trivia: What prevented Paul from visiting the Thessalonians?
Paul predicts that the Jesus will return in his lifetime. He will descend from heaven, the dead will rise, and believers will meet him in the air. This is the main scriptural basis for the "rapture" although that word is not used in the passage or anywhere else in the Bible. (See Mt 24:40-41 for the other source for the rapture.)